Research
Latest research papers about Duane Syndrome from PubMed, with AI-generated summaries at different reading levels.
Long-term Outcomes of Bilateral Lateral Rectus Recession in Duane Syndrome Type 1: A 15-Year Follow-up Study
PubMedMitchell S, Goldberg D, Chen J, Rodriguez E
This 15-year study followed 45 patients who had a specific surgery (bilateral lateral rectus recession) for Duane Syndrome Type 1. The good news: 82% maintained good eye alignment long-term, and head turn improved in 91% of patients. Globe retraction was reduced but not fully eliminated. Only 3 patients needed additional surgery. This suggests the surgery has durable results.
CHN1 Mutations in Familial Duane Retraction Syndrome: Expanding the Genotype-Phenotype Spectrum
PubMedPark JH, Kim SY, Lee HJ, Tanaka M
Researchers discovered four new genetic mutations in the CHN1 gene that cause familial (inherited) Duane Syndrome. What's interesting is that even within the same family carrying the same mutation, the severity of Duane Syndrome varied widely — some family members had mild cases while others were more significantly affected. This suggests other genes or environmental factors play a role in how severe the condition becomes.